Trial
Neurology

Xenon XPF-010-303: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Active recruiting
The primary objective is to assess the effect of XEN1101 versus placebo on reducing PGTCS frequency in subjects with PGTCS.
Trial
Neurology

Xenon XPF-010-302: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures

Active recruiting
The primary objective of this study is to assess the effect of XEN1101 versus placebo on reducing focal seizure frequency.
Trial
Neurology

UCB EP0162: A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting
The purpose of this study is to compare the success of a single admnistration of Staccato alprazolam compared with placebo in rapidly terminating a seizure episode within 90seconds after IMP administration.
Trial
Trial
Neurology

ADCS Benfo: A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients with Early Alzheimer’s Disease (BenfoTeam)

Active recruiting
The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine, to determine whether it delays or slows the progression of the symptoms of early Alzheimer’s disease.
Trial
Internal Medicine

RECHARGE

Active recruiting
To compare the effect of percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG) on survival and improvement in quality-of-life (QOL) in women and minorities.
General Results

Neural Basis of Decisions current lab projects

Algorithmic basis of reward-based decisions in dynamic environment In probabilistic reward foraging task (Fig.1A) animals’ choices tend to reflect the previous rewards, in a way that biases animals’ future choices to options from which they recently received the rewards. In addition to the reward history effects, curiously animals choices also depend on the previous choices, phenomenon that is not easily explained by the current computational models (Fig.1B). We are formulating normative accounts of why choice history effects should persist in animals. The insight into this phenomenon may give
News

Toward the goal

As a father of six, Donald Torry, PhD, has some experience with pregnancy. Helping women who develop preeclampsia has become his life’s work. Preeclampsia is a pregnancy condition in which high blood pressure and protein in the urine develop after the 20th week (late second or third trimester). Preeclampsia develops in 5-10 percent of pregnancies and, aside from anti-hypertensives to try to control spiraling blood pressure, the only “cure” is delivery.
News

Toward the goal

As a father of six, Donald Torry, PhD, has some experience with pregnancy. Helping women who develop preeclampsia has become his life’s work. Preeclampsia is a pregnancy condition in which high blood pressure and protein in the urine develop after the 20th week (late second or third trimester). Preeclampsia develops in 5-10 percent of pregnancies and, aside from anti-hypertensives to try to control spiraling blood pressure, the only “cure” is delivery.
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