Trials and Research Search

Showing: 37 Results

Trial

Neuroscience Institute

18-513: A Randomized Clinical Trial of Andexanet Alfa in Acute Intracranial Hemorrhage in Patients Receiving an Oral Factor XA Inhibitor

Active not recruiting

18-513: The purpose of this study is to evaluate the effect of andexanet alfa (andexanet) versus usual care on the rate of effective homostasis.

Trial

Neuroscience Institute

324-ETD-202: A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Dose-Response Study of SAGE-324 for the Treatment of Essential Tremor

Active recruiting

The primary objective of this study is to evaluate the dose-response relationship of different doses of SAGE-324 on upper extremity tremor in a monotherapy cohort.

Trial

Neurology

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting

The purpose of this study is to compare the success of a single admnistration of Staccato alprazolam compared with placebo in rapidly terminating a seizure episode within 90seconds after IMP administration.

Trial

Neurology

A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Dose-Response Study of SAGE-324 for the Treatment of Essential Tremor

Active recruiting

The primary objective of this study is to evaluate the dose-response relationship of different doses of SAGE-324 on upper extremity tremor in a monotherapy cohort.

Trial

Dermatology

A PHASE 3 OPEN-LABEL, MULTI-CENTER, LONG-TERM STUDY INVESTIGATING THE SAFETY AND EFFICACY OF PF-06651600 IN ADULT AND ADOLESCENT PARTICIPANTS WITH ALOPECIA AREATA

Active not recruiting

The purpose of this study is to evaluate the long-term safety, tolerability, and effectiveness of PF-06651600(Ritlecitinib) in adult and adolescent (12 years and older) participants with Alopecia Areata.

Trial

Pediatrics

A Randomized, Double Blind, Parallel-group, Placebo Controlled Study to Evaluate the Efficacy and Safety of IBP-9414 in Premature Infants 500-1500g Birth Weight in the Prevention of Necrotizing Enterocolitis - The Connection Study

Active recruiting

The purpose of the clinical study is to compare the effectiveness of IBP-9414 treatment against placebo in preventing necrotizing enterocolitis in premature infants.

Treatments: Prevention of necrotizing enterocolitis in premature infants

Trial

Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Active recruiting

The primary objective is to assess the effect of XEN1101 versus placebo on reducing PGTCS frequency in subjects with PGTCS.

Trial

Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures

Active recruiting

The primary objective of this study is to assess the effect of XEN1101 versus placebo on reducing focal seizure frequency.

Trial

Neurology

An Open-Label, Multicenter, Outpatient Extension Study to Evaluate the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting

The primary endpoint of this study is to evaluate the long-term safety and tolerability of Staccato alprazolam.

Trial

Neurology

Annovis - A Randomized, Double-Blind, Placebo-Controlled, Dose-ranging, Multicenter Study of Buntanetap in Participants with Mild to Moderate Alzheimer's Disease

Active recruiting

The purpose of this study is to assess the efficacy and safety of Buntanetap in participants with mild to moderate Alzheimer's Disease participants.

Clinical trials and research studies