News

Notification of a Potential Data Security Incident

Dear Madam/Sir: The Southern Illinois University School of Medicine, (“SIU”) is providing notice pursuant to 815 ILCS 530/25 in connection with an incident that may have involved the personal information of certain Illinois residents. This notice will be supplemented, if necessary, with any new significant facts discovered subsequent to its submission. While SIU is notifying you of this incident, SIU does not waive any rights or defenses relating to the incident or this notice. NATURE OF THE INCIDENT AND CORRECTIVE ACTIONS TAKEN SIU recently discovered that an unknown, unauthorized third party
Trial
Internal Medicine

COSIRA-II: Efficacy of the COronary SInus Reducer in Patients with Refractory Angina II

Active recruiting
To demonstrate the safety and effectiveness of the Shockwave Reducer for treatment of patients with refractory angina pectoris treated with maximally tolerated guideline-directed medical therapy who demonstrate objective evidence of reversible myocardial ischemia in the distribution of the left coronary artery and who are deemed unsuitable for revascularization.
Trial
Cardiology

Dal-GenE-2: A phase 3, double-blind, randomized placebo-controlled study to evaluate the effects of dalcetrapib on cardiovascular (CV) risk in a genetically defined population with a recent Acute Coronary Syndrome (ACS)

Active recruiting
The primary objective of this trial is to evaluate the potential of dalcetrapib to reduce the occurrence of fatal and non-fatal myocardial infarction in subjects with a documented recent ACS and the AA genotype at variant rs1967309 in the ADCY9 gene.
Trial
Cardiology

Dal-GenE-2: A phase 3, double-blind, randomized placebo-controlled study to evaluate the effects of dalcetrapib on cardiovascular (CV) risk in a genetically defined population with a recent Acute Coronary Syndrome (ACS)

Active recruiting
The primary objective of this trial is to evaluate the potential of dalcetrapib to reduce the occurrence of fatal and non-fatal myocardial infarction in subjects with a documented recent ACS and the AA genotype at variant rs1967309 in the ADCY9 gene.
Trial
Cardiology

Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI DTU Trial

Active not recruiting
The purpose of this clinical trial is to demonstrate the safety and effectiveness of primary left ventricular (LV) unloading and a 30-minute delay-to-reperfusion versus current standard of care in reducing infarct size and heart failure-related clinical events in patients presenting with anterior ST-elevation myocardial infarction (STEMI).
Trial
Cardiology

Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI DTU Trial

Active not recruiting
The purpose of this clinical trial is to demonstrate the safety and effectiveness of primary left ventricular (LV) unloading and a 30-minute delay-to-reperfusion versus current standard of care in reducing infarct size and heart failure-related clinical events in patients presenting with anterior ST-elevation myocardial infarction (STEMI).
Trial
Internal Medicine

AstraZeneca BaxPA: A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy and Safety of Baxdrostat in Adult Participants with Primary Aldosteronism

Active recruiting

The purpose of this clinical trial is to learn more about a new, investigational, once daily medication, called baxdrostat, and its ability to lower blood pressure in individuals diagnosed with primary aldosteronism.

Eligible patients include those who currently have a diagnosis of high blood pressure, specifically primary aldosteronism, despite having taken or are currently taking anti-hypertensive medications.

Trial
Simmons Cancer Institute

(2024-02) Specimen Collection from Participants Due for Colorectal Cancer Screening, Surveillance, or Treatment: IMPACT

Active recruiting
This study aims to collect health information along with blood and stool samples (and urine and/or saliva, if applicable) to assist in the development of colorectal cancer screening test(s). Individuals having a colonoscopy (with or without a diagnosis of colorectal cancer) are potentially eligible.
News

PANDAS: Understanding a rare but serious childhood condition

Pandas, the black-and-white bears, are often seen as cuddly, harmless creatures. But in reality, they’re strong, territorial and capable of doing serious damage when provoked. The same goes for PANDAS—not the animal, but a rare condition in children that can be just as surprising and serious.
News

PANDAS: Understanding a rare but serious childhood condition

Pandas, the black-and-white bears, are often seen as cuddly, harmless creatures. But in reality, they’re strong, territorial and capable of doing serious damage when provoked. The same goes for PANDAS—not the animal, but a rare condition in children that can be just as surprising and serious.
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