Laurent Brard, MD

Division Chief, Gynecologic Oncology
Obstetrics and Gynecology
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    About me

    Dr. Laurent Brard is Professor of Obstetrics and Gynecology at Southern Illinois University (SIU) School of Medicine, chief of the Division of Gynecologic Oncology in the Department of Obstetrics and Gynecology, director of the basic research laboratory of the Division of Gynecologic Oncology in the Department of Obstetrics and Gynecology and full member of the Simmons Cancer Institute at SIU. Dr. Brard is a nationally and internationally recognized gynecologic oncologist. He has published extensively in this field, including in the areas of molecular and cancer biology, pre-clinical drug development and novel treatments. His clinical focus is on the treatment of women's cancers. He has conducted investigator-initiated and participated in national (through the Gynecologic Oncology Group (GOG), now NRG Oncology) clinical trials of novel therapeutics with an emphasis on recurrent ovarian cancers. His research interests span five areas: (1) Gynecologic Cancer Health Disparities, (2) Biomarker Discovery in Gynecological Cancer, (3) Cancer Drug Discovery and Development (based on natural or synthetic drugs and drug re-purposing), (4) Ovarian Cancer Genomics (potentially leading to new biomarkers and druggable targets) and (5) Novel therapeutics - clinical trials for gynecologic cancers. He has been the recipient of several NIH and foundation grants to pursue these areas of research. Dr. Brard is principal investigator at the SIU School of Medicine for the P20 CA192987 NIH/NCI grant Addressing Rural Cancer Health Disparities: An SCC-SIUSM Partnership. The goal of this grant is to build a collaborative partnership between SIU School of Medicine and the NCI-designated Siteman Cancer Center (SCC) at Washington University (WUSTL) to promote training and research in the population. 



    Additional languages spoken


    Education & training

    Department of Obstetrics and Gynecology
    Division Chief, Gynecologic Oncology
    Board Certifications
    Gynecologic Oncology
    Medical School
    University of Pittsburgh School of Medicine, Pittsburgh, PA
    Women & Infants Hospital/Brown University, Providence, RI - Internship and Residency in Obstetrics and Gynecology
    Women & Infants Hospital/Brown University, Providence, RI - Gynecologic Oncology

    Clinical locations


    SIU OB-GYN at Simmons Cancer Institute

    315 W. Carpenter St. Springfield, IL 62702 2nd Floor, Clinic C
    Mon - Fri: 8:00 am-4:30 pm

    Hospital privileges

    • HSHS St. John's Hospital, Springfield, IL
    • Memorial Health, Springfield IL


    Research Interests
    Specializes in the diagnosis and treatment of cancers of the female reproductive system, including ovarian cancer, uterine cancer, vaginal cancer, cervical cancer, and vulvar cancer.

    Clinical trials

    Obstetrics and Gynecology

    Endometriosis and the Microbiome

    Active recruiting

    PURPOSE: Endometriosis is an inflammatory disorder in which the tissue that lines the inside of the uterus (the endometrium) spreads to the pelvic and peritoneal cavities outside of the uterus. This is a biological sample collection study examining how bacteria located within the vagina, the urogenital tract and the gastrointestinal tract may affect the development of endometriosis. Investigators are also exploring how an individual’s microbiome affects their estrogen metabolism and inflammation.

    Related articles

    DNA strands

    Simmons Cancer Institute cross-dept. team publishes endometrial cancer study findings

    A team of SIU medical research scientists recently had their cancer study results published in a special issue of the international, peer-reviewed, open access journal Life.